事件记录
面试官: Testosterone therapy, generally speaking it's safe, but there are some side effects. 你想知道什么? Why is it important to have a doctor part of your treatments and not just buying it off a TV ad? 大发娱乐下节课再讲这个.
播音员: Medical news and research from University of Utah physicians and specialists you can use for a happier healthier life. 您正在收听的是范围.
睾酮治疗有哪些风险?
面试官: 如果你正在接受睾丸激素治疗, it's important to be regularly monitored by a physician to avoid potential risk. Dr. 吉姆酒店 is a urologist and a men's health expert at University of Utah Health Care.
假设我是一个男人. I saw the TV ad for testosterone treatments and now I'm taking them. 有可能存在的风险吗?
不育
Dr. 酒店: I mean I think the biggest thing we see very frequently, and I define frequently as I probably see one to two guys a week with this, 睾丸素会让男人不育吗. It's actually been trialed as a male birth control. 它只对90%到95%的男性有效. So it didn't actually make it as male birth control. 但这是最重要的. It will drop your sperm count to zero in most instances.
红细胞计数升高
The other issue is that it can raise your red blood cell count in some men to unsafe levels. 特别是注射可以做到这一点. 它还会导致液体潴留. Theoretically we used to think that it would increase your risk of prostate cancer. But there really isn't a lot of data to actually support that.
增加中风或心脏病发作的风险
And then there's been a lot of data about cardiovascular disease, testosterone and increasing the risk of stroke or heart attack. 事实证明确实如此, 主要研究表明了这一点, which is a paper in a very prominent medical journal, has been shown to be methodologically flawed in a number of different things. And actually there's a lot of data that shows that men with testosterone actually do better from a cardiovascular disease standpoint.
I think generally speaking it's a very safe drug as long as things are monitored appropriately. We check labs on our patients every three to six months for the first year and then annually thereafter. Generally speaking we have very few, if any, adverse events from men being on it. So that in a nutshell are what the major concerns are.
睾酮治疗危险吗？?
面试官: So the people that are probably the target for the television commercials tend to be older. So they might not be concerned about their child rearing days are done. 有危险吗？? I always understood that there just wasn't enough research to say whether or not it's safe at this point. And I hear a lot of comparisons to estrogen treatments in women.
Dr. 酒店: Yeah, so there have been some huge trials done on estrogen treatments. One of the big issues is with that is increasing the risk of blood clots.
Testosterone treatments actually raises estrogen levels in men as well. 这可能是一个问题. That can get to an unsafe level especially in overweight men. Their fatty tissue has an enzyme in it that will convert testosterone to estradiol which is a female hormone and that can get to unsafe levels.
I think the big issue with testosterone is that we have patients who have been on testosterone for 5, 10, 15年了，大发娱乐还没有跟进. We don't have the research to know what the exact effects are for being on it for that long. We think generally speaking it's very safe as long as it's used in a reasonable and measured fashion.
与医生交谈的重要性
面试官: So originally in this conversation I was going to take it in the direction of, 有人在电视上看到了这个广告, they're getting the creams in the mail now and I was thinking it's a dangerous thing. But it sounds like you're saying it's not a dangerous thing.
Dr. 酒店: I think if it's monitored appropriately and men are on it for the right reasons, I think it can make a big difference in their quality of life.
面试官: 所以如果我是因为电视广告上的, it's a good idea at some point to go to a urologist and have some labs done.
Dr. 酒店: 是的,肯定. We see a lot of people who are not really appropriately managed. There's a lot of these testosterone clinics that never see the patient and maybe have a phone interview and I think if men are on testosterone they need to see a physician regularly, 对适当的实验室进行监控, 要知道这会让他们不育.
I would say no man of reproductive age who is planning on having children in the future should be on testosterone. There are alternatives that we can use that men have low testosterone and symptoms that are of reproductive age and can boost their testosterone and actually improve, 不伤害他们的生育能力.
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